Folklore Clinical Variant Interpretation MCP

Free hosted MCP server from Helena Bioinformatics for human genetic variant research: get evidence and an automated ACMG/AMP classification for one public germline variant (GRCh38 SNVs and small indels under 50 bp), find gene-disease associations, and search linked scientific literature. No account or key. Public variants only, never patient data; a research aid that needs qualified professional review, not a diagnosis.

🔬 ResearchReader submission1Updated 2026-09-11By Helena BioinformaticsLicense: Apache-2.0Auth: None: free hosted server, no account or API keyGitHub ↗

Found viaWebReader submission GitHubhelena-bioinformatics/folklore-mcp (GitHub) MakerFolklore MCP setup WebOfficial MCP registry entry

Test results

No full client pass yet

Claude CodeNot tested yet—

CursorNot tested yet—

Claude DesktopNot tested yet—

ChatGPT (Codex)Not tested yet—

Protocol: not tested

Install

claude mcp add --transport http folklore https://api.helena.bio/folklore/v1/mcp

No account or key. Not yet confirmed by us.

{
  "mcpServers": {
    "folklore": { "url": "https://api.helena.bio/folklore/v1/mcp" }
  }
}

From the maker's setup page. Not yet confirmed by us.

[mcp_servers.folklore]
url = "https://api.helena.bio/folklore/v1/mcp"

Add to ~/.codex/config.toml. From the maker's setup page.

From the maker’s docs (checked Oct 29, 2026). Our harness hasn’t run this server yet, so these steps are not verified by us.

Not connecting? Troubleshooting: Claude Code · Cursor · Claude Desktop · ChatGPT (Codex)

Test history

No test runs yet.